GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs1056667 | 1 | rs6456733 | chr6:26566804 | BTN2A3 | chr6:26422317-26431927:+ | 0.18 | 4.31 | 2.0E-5 | Educational attainment |
| THCA | cis | rs1056667 | 1 | rs6456733 | chr6:26566804 | HCG11 | chr6:26521934-26527610:+ | -0.22 | -4.28 | 2.24E-5 | Educational attainment |
| THCA | cis | rs1056667 | 1 | rs6456733 | chr6:26566804 | HMGN4 | chr6:26538572-26547162:+ | -0.16 | -4.13 | 4.35E-5 | Educational attainment |
| THCA | cis | rs1056667 | 1 | rs6456733 | chr6:26566804 | LOC100270746 | chr6:26987146-26988085:- | -0.15 | -3.49 | 0.000531 | Educational attainment |
| THCA | cis | rs1056667 | 1 | rs6456733 | chr6:26566804 | ZNF322A | chr6:26634612-26659963:- | -0.16 | -4.63 | 4.82E-6 | Educational attainment |
| THCA | cis | rs1056667 | 1 | rs6456734 | chr6:26566965 | BTN2A3 | chr6:26422317-26431927:+ | 0.18 | 4.31 | 2.0E-5 | Educational attainment |
| THCA | cis | rs1056667 | 1 | rs6456734 | chr6:26566965 | HCG11 | chr6:26521934-26527610:+ | -0.22 | -4.28 | 2.24E-5 | Educational attainment |
| THCA | cis | rs1056667 | 1 | rs6456734 | chr6:26566965 | HMGN4 | chr6:26538572-26547162:+ | -0.16 | -4.13 | 4.35E-5 | Educational attainment |
| THCA | cis | rs1056667 | 1 | rs6456734 | chr6:26566965 | LOC100270746 | chr6:26987146-26988085:- | -0.15 | -3.49 | 0.000531 | Educational attainment |
| THCA | cis | rs1056667 | 1 | rs6456734 | chr6:26566965 | ZNF322A | chr6:26634612-26659963:- | -0.16 | -4.63 | 4.82E-6 | Educational attainment |
| THCA | cis | rs9368849 | 1 | rs6457805 | chr6:35120443 | UHRF1BP1 | chr6:34759794-34853117:+ | -0.11 | -3.74 | 0.000203 | Airway responsiveness in chronic obstructive pulmonary disease |
| THCA | cis | rs1983891 | 1 | rs6458228 | chr6:41543793 | MDFI | chr6:41604930-41621981:+ | 0.18 | 5.44 | 8.71E-8 | Prostate cancer |
| THCA | cis | rs9369898 | 1 | rs6458685 | chr6:49379536 | CENPQ | chr6:49431096-49460820:+ | -0.32 | -6.8 | 3.23E-11 | Homocysteine levels |
| THCA | cis | rs9369898 | 1 | rs6458688 | chr6:49406056 | CENPQ | chr6:49431096-49460820:+ | -0.32 | -6.85 | 2.3E-11 | Homocysteine levels |
| THCA | cis | rs9473555 | 1 | rs6458690 | chr6:49411619 | CENPQ | chr6:49431096-49460820:+ | -0.26 | -5.49 | 6.51E-8 | Folate pathway vitamin levels |